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IONIS PHARMACEUTICALS INC. (IONS) — Hedge Fund Ownership Q4 2025

IONS
Q4 2025Q3 2025Q2 2025Q1 2025
  • IONIS PHARMACEUTICALS INC. (IONS) is held by 2 of 82 tracked hedge funds, with Third Avenue Management (16%) and Tweedy, Browne (16%) holding the largest stakes, indicating limited hedge fund interest relative to peers.
  • The biggest decreases in IONS holdings came from Third Avenue Management (-15%) and Tweedy, Browne (-15%), suggesting profit-taking or de-risking.
  • Overall, hedge funds decreased exposure to IONIS PHARMACEUTICALS INC. (IONS) by -15% vs the prior quarter and -24% vs prior year.
# Fund % of Portfolio † Shares † Shares vs Prior Quarter † Shares vs Prior Year † Aggregate Value † Reported Price * Option
1
Third Avenue Management
15.74% 2.5M -15.04% -24.13% $195.0M $79.11
2
Tweedy, Browne
Tweedy, Browne Co LLC
15.74% 2.5M -15.04% -24.13% $195.0M $79.11
2 Total 4.9M -15.04% -24.13% $390.0M
* Reported price is not an actual purchase or sale price. It is the price as of the last portfolio date.
† Portfolio value, share counts, and period-over-period changes exclude options positions (PUT/CALL), which are shown in the Option column for reference only.